HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

John J Mullins Selected Research

Malignant Hypertension

5/2011Direct renin inhibition with aliskiren normalizes blood pressure in Cyp1a1-Ren2 transgenic rats with inducible angiotensin ii-dependent malignant hypertension.
2/2011Enhancement of renin and prorenin receptor in collecting duct of Cyp1a1-Ren2 rats may contribute to development and progression of malignant hypertension.
11/2010Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
6/2010Transient induction of ANG II-dependent malignant hypertension causes sustained elevation of blood pressure and augmentation of the pressor response to ANG II in CYP1A1-REN2 transgenic rats.
4/2010AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet.
6/2009Angiotensin-converting enzyme is a modifier of hypertensive end organ damage.
1/2008Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension.
11/2007Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats.
6/2007Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
9/2006Cyclooxygenase-2 inhibition normalizes arterial blood pressure in CYP1A1-REN2 transgenic rats with inducible ANG II-dependent malignant hypertension.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


John J Mullins Research Topics

Disease

36Hypertension (High Blood Pressure)
01/2019 - 07/2003
14Malignant Hypertension
05/2011 - 02/2004
9Hypertrophy
10/2017 - 07/2003
8Fibrosis (Cirrhosis)
05/2017 - 05/2002
4Diabetic Nephropathies (Diabetic Nephropathy)
05/2017 - 03/2012
4Hyperglycemia
05/2017 - 04/2006
4Albuminuria
11/2015 - 01/2012
4Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2012 - 07/2003
4Cardiomegaly (Heart Hypertrophy)
07/2010 - 05/2002
3Inflammation (Inflammations)
05/2017 - 06/2006
3Hyperplasia
02/2009 - 07/2003
3Obesity
05/2004 - 07/2003
3Insulin Resistance
05/2004 - 07/2003
3Dyslipidemias (Dyslipidemia)
05/2004 - 07/2003
3Abdominal Obesity
05/2004 - 07/2003
2Wounds and Injuries (Trauma)
01/2022 - 07/2007
2Necrosis
10/2017 - 10/2013
2Type 2 Diabetes Mellitus (MODY)
05/2016 - 04/2004
2Cardiovascular Diseases (Cardiovascular Disease)
04/2016 - 01/2008
2Bradycardia
12/2014 - 10/2013
2Hypokalemia
03/2011 - 02/2009
2Proteinuria
11/2010 - 11/2007
2Cushing Syndrome
10/2009 - 04/2004
1Reperfusion Injury
01/2020
1Adenoma (Adenomas)
10/2017
1Kidney Diseases (Kidney Disease)
05/2017
1Hypotension (Low Blood Pressure)
02/2016
1Hypoxia (Hypoxemia)
11/2015
1Cicatrix (Scar)
12/2014
1Ventricular Dysfunction
12/2014
1Heart Block
12/2014
1Hemorrhage
10/2013
1Polyuria
08/2012
1Peritonitis
06/2012
1Metabolic Diseases (Metabolic Disease)
03/2012
1Vascular System Injuries
01/2012
1Barotrauma
01/2012

Drug/Important Bio-Agent (IBA)

19ReninIBA
12/2014 - 05/2002
16indole-3-carbinolIBA
12/2014 - 10/2005
10Angiotensin IIIBA
11/2015 - 07/2003
10GlucocorticoidsIBA
03/2012 - 07/2003
8SodiumIBA
04/2016 - 01/2008
8EnzymesIBA
07/2015 - 07/2003
711-beta-Hydroxysteroid Dehydrogenase Type 1IBA
05/2010 - 07/2003
6SaltsIBA
04/2016 - 07/2003
6MineralocorticoidsIBA
07/2015 - 01/2008
5AldosteroneIBA
10/2017 - 11/2007
5Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
04/2016 - 11/2007
5HydrocarbonsIBA
06/2010 - 10/2005
4Oxidoreductases (Dehydrogenase)IBA
07/2015 - 01/2011
4Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2010 - 10/2003
3Adrenocorticotropic Hormone (ACTH)FDA Link
10/2017 - 10/2009
3Messenger RNA (mRNA)IBA
08/2012 - 05/2004
3AngiotensinsIBA
05/2011 - 04/2010
3AngiotensinogenIBA
02/2011 - 05/2004
3XenobioticsIBA
03/2010 - 12/2006
3Peptides (Polypeptides)IBA
12/2009 - 02/2006
3Cytochrome P-450 CYP1A1 (CYP1A1)IBA
11/2007 - 04/2005
2CollagenIBA
05/2017 - 06/2013
2Streptozocin (Streptozotocin)FDA Link
12/2014 - 03/2012
2Proteins (Proteins, Gene)FDA Link
11/2013 - 02/2011
2Hydralazine (Apresoline)FDA LinkGeneric
01/2013 - 12/2006
2Biological ProductsIBA
03/2012 - 06/2009
2Insulin (Novolin)FDA Link
03/2012 - 05/2004
2Hydrochlorothiazide (Esidrix)FDA LinkGeneric
01/2012 - 12/2006
2Spironolactone (Aldactone)FDA LinkGeneric
01/2012 - 11/2007
2Prorenin ReceptorIBA
02/2011 - 01/2008
2candesartanIBA
11/2010 - 12/2006
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2008 - 09/2006
2CorticosteroneIBA
03/2007 - 10/2003
2Superoxides (Superoxide)IBA
10/2005 - 04/2005
14- (2,6- dichlorobenzoylamino)- 1H- pyrazole- 3- carboxylic acid piperidin-4-ylamideIBA
01/2022
1alvocidib (flavopiridol)IBA
01/2022
1Lactic Acid (Lactate)FDA LinkGeneric
01/2020
1Collagen Type I (Type I Collagen)IBA
01/2020
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020
1SterolsIBA
10/2017
1triptolideIBA
10/2017
1Cyclic AMP (AMP, Cyclic)IBA
10/2017
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
05/2017
1Purinergic P2X7 ReceptorsIBA
05/2017
1Epidermal Growth Factor (EGF)IBA
05/2016
1Biomarkers (Surrogate Marker)IBA
05/2016
1Cyclin-Dependent Kinases (cdk Proteins)IBA
12/2015
1RNA Polymerase II (RNA Polymerase B)IBA
12/2015
1Positive Transcriptional Elongation Factor BIBA
12/2015
1Blood Glucose (Blood Sugar)IBA
12/2014
1Tissue Inhibitor of Metalloproteinase-1IBA
12/2014
1Tight Junction ProteinsIBA
11/2013
1Claudin-5IBA
11/2013
1Losartan (Cozaar)FDA LinkGeneric
01/2013
1OsteopontinIBA
01/2013
1ProlactinIBA
06/2012
1LuciferasesIBA
06/2012
1ThiazidesIBA
01/2012
1SymportersIBA
01/2012
1Sodium ChlorideFDA LinkGeneric
01/2012

Therapy/Procedure

5Therapeutics
01/2019 - 06/2006
2Lasers (Laser)
12/2014 - 10/2013
1Laser Therapy (Surgery, Laser)
12/2014